Fusion event
HBV-chr12 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
18360532/18207598 (Hg38)
Nearest miRNA
hsa-mir-1244-3/Upstream/533326; hsa-let-7i/Downstream/6004823;
Upstream sequence
atacaccatggaatactatacagccataaaaaagaatgagttaatgtcctttgcagggacatggatgacactagaaactatcattctcagcaaactaaca
Downstream sequence
cccagccactcaagctacaaacttgaaaaccatctttgactcctcccttttccAATCAGTTTGGAAAAAGGTTTATATCTTAACCTTTTTAAGAAAAACA
Target sequence
GTTGCAAGAGAAAGTCTTGTCATTACAAAACATCAAGACTTTAAGGAAAGAAAATCAATCTCTAGGTGTGCtttttttttttttcctttcttttcttgtcttAAGGAATGAGGTATCCATAGCTTGCCTGAGGATAATCCTTCACCTGTGTTTGAGATTCACAacctgctatctcaggggttttattctaacagtttcaactaacagccaaataccaatcattgccaaacctacatctctagctctgaatttttt
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.