Fusion event
HBV-CRYL1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
21031210/20457071 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4499/Upstream/23136; hsa-mir-1267/Downstream/3705345;
Upstream sequence
gtgCTGTTATAAATTTTTCAGTGGGGAGGTGGTTGCAAAGGTTACAGCAGATCAGCTATTGCTGGCTAGCCTCCAAATTGGTCTCTAATTTGAGGTTGAT
Downstream sequence
AGTCCCAGCTTACCCACCTCAgcccagcctctgtggtccagctctggcccagggcagcctagagaacaggaagtcatcctccatccactggaccacagcc
Target sequence
TCCTGGGCTCTTCCAGTGCAGACTGCCAGCAGGATATGAGTGCACTGGCAGCCCAGCTCAAGGATTCCAGCTTCCAGTCCCAGCTTGAG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.