Basic Information
VIS ID
TVIS10019249
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr13
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
76537260/75963124 (Hg38)
End
76537359/75963223 (Hg38)
Fragile sites / regions
FRA13E
Nearest miRNA
hsa-mir-1297/Upstream/9744800; hsa-mir-1267/Downstream/1734789;
Nearest TSS
ENST00000623511/Upstream/27992; ENST00000646457/Downstream/51278;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/326047, chr13-CpG: 195/Downstream/921964
Nearby gene
LMO7DN-IT1
Upstream sequence
agtcatcagtactttgcctctcagctgcacacccacgcttctttgccctgctttgtgacagtaggagtctggTGGGATGAAGGGGCTTCCCTTCCTCTCT
Downstream sequence
TTTGAAGATTTTTTTCTCAATAATTCTTATGTTAATGGTTTAGATTGAAGGCCTTATCCTCTGGAGTATAAGTCTTTTCAAAGTCCAAGAAGTGATTTCT
Target sequence
GTCTGTTGTCTAACAACAACCAAAAGACACTTAATTAGTACCCCAGGGAAGGCAGATTTATTGTGTTATTTTCAATATCTCTTCAATATCCTTTGGTGT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate