Basic Information
VIS ID
TVIS10019251
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
24775153/24305947 (Hg38)
End
24775189/24305983 (Hg38)
Location type
Exonic
Target gene
CIDEB ; NOP9
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-208a/Upstream/162382; hsa-mir-1185-1/Downstream/2602659;
Nearest TSS
ENST00000550708/Upstream/213; ENST00000530080/Downstream/478;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/5789, chr14-CpG: 108/Downstream/4685
Upstream sequence
CAATTACATTTACTGTTTCCACTTCTAGTCTCCTTACAGAAGACTATTTGGAGGAGGGGTGGTTtcttctttttgcagcttcttaaattgtacacctcat
Downstream sequence
AACTCATAGAGTAGAGCCCGTAGAATGTGGCTTTGACATTCAGGCTGCCAAAGAGGTCTCGAGGGTTTTGCTTGTACACGTCAAAGGTGAATCGGGCGAT
Target sequence
TGAGTACTTTCTTTGGGCCAAGTCCTTGAAAGTCAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate