Basic Information
VIS ID
TVIS10019265
Fusion event
HBV-PROX1-AS1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
214112788/213939445 (Hg38)
End
214112789/213939446 (Hg38)
Location type
Intron4
Target gene
PROX1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/1861760; hsa-mir-1182/Downstream/6178407;
Nearest TSS
ENST00000473358/Upstream/12791; ENST00000607726/Downstream/43735;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/549830, chr1-CpG: 42/Downstream/40425
Upstream sequence
GTGGTGGAAGTCCTTGATGGGGGcagtaaacaaagtcaaacggttaagagtttggactgtgtggttggacttcttgggttggaatttccacagttctact
Downstream sequence
agtgtactaatcctgtcttctgccgtacgcaagccaagctcttgctaaacctgtccaacaaattcttaatgtcagctataatatttttaggttatataat
Target sequence
g
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate