RYR2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019268
Fusion event
HBV-RYR2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
237471450/237308150 (Hg38)
End
237471450/237308150 (Hg38)
Location type
Intron2
Target gene
RYR2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-25-3p ; hsa-mir-17-5p ; hsa-let-7c-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1455090; hsa-mir-3123/Downstream/162969;
Nearest TSS
ENST00000473358/Upstream/37653; ENST00000609253/Downstream/366614;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/264806, chr1-CpG: 22/Downstream/475737
Upstream sequence
tttggaaacactctgtttgtaaagtctgcacgtagatattttgaccacttagaggccttctttggaaacggttttttctcatgtaaggctagacagaaga
Downstream sequence
ATATTCCATTTCCTTCAAAAGTATTTTGACCTAATAAACAAAACCTCTCTGAGTGCTAGATAATTCTTATAAATGTAATACATTGAACTTATAATTACAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate