Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019274
Fusion event
HBV-CCDC93 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
End
118740907/117983331 (Hg38)
Location type
Intron17
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-7977 ; hsa-mir-561-5p ; hsa-mir-4474-5p ; hsa-mir-6787-3p ; hsa-mir-138-1-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-3922-5p ; hsa-mir-6875-3p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-4753-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-642a-5p ; hsa-mir-22-5p ; hsa-mir-4703-3p ; hsa-mir-130b-5p ; hsa-mir-1248 ; hsa-mir-6769b-3p ; hsa-mir-3183 ; hsa-mir-4723-3p ; hsa-mir-5088-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-5584-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-3168 ; hsa-mir-4280
Nearest miRNA
hsa-mir-1285-2/Upstream/4261963; hsa-mir-10b/Downstream/9440206;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/122744, chr2-CpG: 101/Downstream/29952
Upstream sequence
AAGCCCACTGAGCTACAGACACTATCTGAAGGAAGGCTTCAATTTCAGCTCTGTCTATGATATAAATGATTTACAAACAGGGACACAGAGTTATGAAAAC
Downstream sequence
gtcacacttctgtggttttccccccacacaataaattatgtatgccattttctcctgttaatctgccttttgtcagttcattttcagtgaaccttcagag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.