Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019276
Fusion event
HBV-TMEFF2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
End
192880130/192015404 (Hg38)
Location type
Intron5
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-7641 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-7106-3p ; hsa-mir-4252 ; hsa-mir-494-3p ; hsa-mir-6849-3p ; hsa-mir-4691-3p
Nearest miRNA
hsa-mir-10b/Upstream/2882293; hsa-mir-1244-1/Downstream/14767830;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/133134, chr2-CpG: 140/Downstream/178865
Nearest cancer related gene
TMEFF2(TSG, No orient, 0)
Upstream sequence
TTTCTAACTGTTCTCTGTTCCCGGAACCGAAATCACCTGTTGCATGGTAAGGCACTTACTTCATTTCCCAAAGAAAAGGAGTGAAAGATAGCAAAAACTA
Downstream sequence
TAATCTGCGATATGTGTGCCCCTTTAAAATAATTTATGATTAAAGTCTGCAACTGTGGCTAAATTGCACACATTAGGGTCTACTGTTTTTTAAAGGCTAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.