Basic Information
VIS ID
TVIS10019277
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204660695/203795972 (Hg38)
End
204660695/203795972 (Hg38)
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/14662861; hsa-mir-1244-1/Downstream/2987262;
Nearest TSS
ENST00000437798/Upstream/89424; ENST00000295854/Downstream/71814;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/260526, chr2-CpG: 83/Downstream/749244
Nearby gene
CTLA4
Upstream sequence
CTTGGAAGCCAGTGATCGTCTCAGTCTTGGTTCTCCAGCTAATGGTGATGGTGGTCTCAGTAGCATCTGTCACACGAGCCCTTCTTGGTGGGCTGACATC
Downstream sequence
aaaaggaaatagagtgcaccagaatactaacaatggttgtttttcaaaagtgatattatgtgtatttataaatagttatttctattattttctgttctgt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate