Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019280
Fusion event
HBV-MREG integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
End
216852196/215987473 (Hg38)
Location type
Intron3
Target gene
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-130b-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-1307-3p ; hsa-mir-130a-3p ; hsa-mir-144-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-3925-5p ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-4638-5p ; hsa-mir-4712-3p ; hsa-mir-488-5p ; hsa-mir-504-3p ; hsa-mir-589-5p ; hsa-mir-6812-3p ; hsa-mir-95-5p
Nearest miRNA
hsa-mir-10b/Upstream/2229314; hsa-mir-1244-1/Downstream/1913040;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/551336, chr2-CpG: 51/Downstream/25703
Upstream sequence
CTGCTCCCCATCCTCAGATATCTGATAGACATTTACAATGTATTTTCGGCCAGGAAGCAGGTCAGGGATGTTCACAGAAGTGGCTGTGCTTGGAAGATCT
Downstream sequence
ggatctcgtgagccacccacctcagcctcccaaagtgctgggattacaggcgttagccaccatacccggcAACATAAGCAACTTTTAAAAACTACATTAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.