VISDB Viral Integration Site DataBase

VIS ID

TVIS10019285

Fusion event

HBV-TGFBR2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr3

Cytoband

p24.1

Reference genome

Start

End

30663464/30621972 (Hg38)

Location type

Intron1

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-20a-5p ; hsa-mir-204-5p ; hsa-mir-17-5p ; hsa-mir-18a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-590-5p ; hsa-mir-92a-3p ; hsa-mir-302b-3p ; hsa-mir-372-3p ; hsa-mir-106a-5p ; hsa-mir-370-3p ; hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-34b-5p ; hsa-mir-373-3p ; hsa-mir-145-5p ; hsa-mir-630 ; hsa-mir-211-5p ; hsa-mir-655-3p ; hsa-mir-130a-3p ; hsa-mir-142-5p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-548c-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-5590-3p ; hsa-mir-1276 ; hsa-mir-216a-5p ; hsa-mir-551b-5p ; hsa-mir-1200 ; hsa-mir-544b ; hsa-mir-5095 ; hsa-mir-6758-3p ; hsa-mir-7151-3p ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-610 ; hsa-mir-3978 ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-449c-5p ; hsa-mir-1253 ; hsa-mir-1910-3p ; hsa-mir-2682-5p ; hsa-mir-6511a-5p ; hsa-mir-6770-5p ; hsa-mir-6806-5p ; hsa-mir-1827 ; hsa-mir-4316 ; hsa-mir-9-5p ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-595 ; hsa-mir-4438 ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4324 ; hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-6867-5p ; hsa-mir-6818-5p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-488-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6777-3p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-7159-5p ; hsa-mir-505-3p ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-3065-5p ; hsa-mir-3200-5p ; hsa-mir-7849-3p ; hsa-mir-606 ; hsa-mir-570-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-202-5p ; hsa-mir-181c-5p ; hsa-mir-520a-3p ; hsa-mir-23b-5p ; hsa-mir-302d-3p

Nearest miRNA

hsa-mir-12127/Upstream/4957033; hsa-let-7g/Downstream/539732;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/14583, chr3-CpG: 29/Downstream/272583

Nearest cancer related gene

TGFBR2(TSG, No orient, 0)

Upstream sequence

gaaaactccatgtatgttaaacttgtgcaataaacagcttgtgttggccgggcgcggtggctcatacctgtaatcccagcactttgggaggccaaggtgg

Downstream sequence

GACTAAGTATTAGATGTCTGTGTAAGCCATTTTCTGTGAGTCAAAACAATTTTGTTCTTCCTTATGTCTTTCTTCAGAGGTACATCTTTAATAAGTTCTG