Basic Information
VIS ID
TVIS10019295
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
90898694/89977543 (Hg38)
End
90898694/89977543 (Hg38)
Fragile sites / regions
FRA4E
Nearest miRNA
hsa-mir-12113/Upstream/2676960; hsa-mir-1243/Downstream/9019844;
Nearest TSS
ENST00000502981/Upstream/26098; ENST00000508550/Downstream/149992;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/139824, chr4-CpG: 123/Downstream/149717
Nearby gene
MMRN1
Upstream sequence
ACAGTAATATATTTTTTGCTTACTTTTCCTGCTGTGCTCATGTTGATTCTGTCTTCTCTGCAGACCAGGAGACTGGTGAGTCCTTGTGGATTTCTTCCCT
Downstream sequence
AAGCTGTTTTTCTTACATGATCAGGTACCTTGGCTATGGTCTAGGGAAACCACAGGTTTCCAACTTAATCCACATAATTCCTGCATACTTGACTTAGTTA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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