Basic Information
VIS ID
TVIS10019298
Fusion event
HBV-IQCM integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
q31.23
Reference genome
GRCh37/hg19
Start
150631076/149709924 (Hg38)
End
150631079/149709927 (Hg38)
Location type
Intronic
Target gene
IQCM
Nearest miRNA
hsa-mir-12113/Upstream/1927256; hsa-mir-1305/Downstream/2779400;
Nearest TSS
ENST00000502981/Upstream/43867; ENST00000505586/Downstream/105887;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1264020, chr4-CpG: 161/Downstream/368171
Nearby gene
DCLK2
Upstream sequence
gtaaaaataagtagccaaaagtatgtaaacttgaattatttatcttcagtaatgttttagtattgtatcttatttataaatggtctagatatttaatgca
Downstream sequence
GTTTCAAGAAAGTAAAGCTTGCAGGCCAACCAAAAAGGGAGTGCAACCTCTTATAACAGTGAAAATCAACTCTTTGAGAGTAACATTCTGTTTTCAAGGG
Target sequence
ACA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate