Fusion event
HBV-FGB integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
155493584/154572432 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/2035439; hsa-mir-1305/Downstream/4556370;
Upstream sequence
ggttaggggttagggtcagggtcagggtcagggtcagggtcaggggtagggtagggttagggttagggttagggttagggttagggttgggttagggtta
Downstream sequence
taaagagtatgtagtttatataacatttctacttagcactctccacttagcaacctccatttaacccaaaataaaaggccttggttccttgcacatcctg
Target sequence
TTAACTTTTGACCTGGTTTCTCTGCCACAAGTTCTGTCCCACTGGAGCCCATACTCACCTACCGCTTTGCCATCACATTTAACAGAAAACTCTTATCAACTTACTTCCTGCTTAACATTAGCTCCTTCCTATCTATATCCAAATTTCTTAAATTCAAATTTTTTAGCTGGAGTAAAAATGGTCCCAGTACCATTTCCTGTTCCCTTCACTATAACCTACATTTTTGTCACATTAAGTTTTTCCCCATTCCAGGAC
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.