Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019309
Fusion event
HBV-DAAM2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
Start
End
39795360/39827584 (Hg38)
Location type
Intron1
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-19b-3p ; hsa-mir-18a-5p ; hsa-mir-335-5p ; hsa-mir-4707-3p ; hsa-mir-7108-3p ; hsa-mir-589-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6752-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p
Nearest miRNA
hsa-mir-1236/Upstream/753114; hsa-mir-10398/Downstream/1771139;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/34845, chr6-CpG: 17/Downstream/74219
Upstream sequence
tatctagtgtgtttctttagctctatctacaggcattgtgatatgtgttgtgtctagcatgctttgaaattggcttataaataaaagagcactcataaat
Downstream sequence
CCTGGTAGGATGCAGGGGCCTGGGCTTCAGAAACAGTGGCTGGAGGATTCTCCCTGACTCTTTTCCTTGGGGTCCTCATGCCTGGATTACTCTTCAGGGT
Target sequence
TGTGGAATGGTGCTTCACCACCCCAGGGAATGGTGGCCCTCACTCACGCCTTGGCTCTGTGTGTGTGGGCTCATGGAGGTGCCCCCGGG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.