Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019322
Fusion event
HBV-DLC1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
Start
End
13079223/13221714 (Hg38)
Location type
Intron13
Target gene
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-mir-16-5p ; hsa-let-7d-5p ; hsa-mir-877-3p ; hsa-mir-30c-5p ; hsa-mir-20a-5p ; hsa-mir-200a-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-5683 ; hsa-mir-1273e ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-6828-5p ; hsa-mir-5688 ; hsa-mir-646 ; hsa-mir-495-3p ; hsa-mir-548c-3p ; hsa-mir-8065 ; hsa-mir-203a-3p ; hsa-mir-3163 ; hsa-mir-4496 ; hsa-mir-5680 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-340-5p ; hsa-mir-4450 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-1205 ; hsa-mir-511-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-576-3p ; hsa-mir-4325 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4671-3p ; hsa-mir-633 ; hsa-mir-3976 ; hsa-mir-2278 ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-3666 ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6754-3p ; hsa-mir-197-3p ; hsa-mir-412-3p ; hsa-mir-1266-3p ; hsa-mir-3140-5p ; hsa-mir-6823-5p ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-6753-5p ; hsa-mir-578 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-744-3p ; hsa-mir-29b-2-5p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6740-5p ; hsa-mir-5087 ; hsa-mir-4778-3p ; hsa-mir-483-3p ; hsa-mir-429
Nearest miRNA
hsa-mir-124-1/Upstream/494410; hsa-mir-10400/Downstream/1631724;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/88309, chr8-CpG: 53/Downstream/54619
Nearest cancer related gene
DLC1(TSG, No orient, 0)
Upstream sequence
cacagaaagtacagccttgcctacaccttgatttcatacttttgccacccaggactgtgagacaataaatttctgctgttttaatccacccagtttgtga
Downstream sequence
tgtgtgtgtgtgtatatatatatatatatatgataaaccattatatataatattaatatattaatataaaacacatcaatatattaatataaaatacata
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.