PBLD _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019336
Fusion event
HBV-PBLD integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
70089764/68330007 (Hg38)
End
70089764/68330007 (Hg38)
Location type
Intron9
Fragile sites / regions
FRA10C
Target gene
PBLD
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-374a-5p ; hsa-mir-4690-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-6746-3p ; hsa-mir-4438 ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1265/Upstream/926597; hsa-mir-107/Downstream/3460740;
Nearest TSS
ENST00000439456/Upstream/23128; ENST00000467249/Downstream/1167;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/98241, chr10-CpG: 128/Downstream/1291
Upstream sequence
gaaagggtgggaagggggtgagggataaaagactgtaaattgagttcagtgtatactgctcaggagatgcgtgtacctcaaatttcacaaatcaccacta
Downstream sequence
CATTGGTTGTGAGAGGAGGGTCTGGTGAAATTCCATACCGATTGTCCGTGTGTGAGCTGCTGTACCATAGCCTCCCTGCAGAACCACTAACCTGTCAAAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate