EXOC6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019338
Fusion event
HBV-EXOC6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94811860/93052103 (Hg38)
End
94811860/93052103 (Hg38)
Location type
Intron20
Fragile sites / regions
FRA10D
Target gene
EXOC6
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-31-5p ; hsa-mir-4668-3p ; hsa-mir-6739-3p ; hsa-mir-6853-3p ; hsa-mir-1206
Nearest miRNA
hsa-mir-107/Upstream/3459276; hsa-mir-1287/Downstream/3012212;
Nearest TSS
ENST00000439456/Upstream/54629; ENST00000285949/Downstream/8323;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/202821, chr10-CpG: 255/Downstream/8166
Upstream sequence
ACTAACAGAAGCAAATCTGTAACCAGCAAATCTTTTTCATAAAAATTAAGAAATTATCAAAATGAATTTAGAAAATTATATCCTAAAAAGACTTATTTCT
Downstream sequence
AACAGAACACAAGAAAAATCCTTCATTAAGGGTCACTACCAATCTGTTAAAACATGAGTGGGTGTGGGTACACTTCCAGCCCTTCTGTCAACGCTTGCAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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