Basic Information
VIS ID
TVIS10019343
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
4402703/4381473 (Hg38)
End
4402792/4381562 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/525332; hsa-let-7a-2/Downstream/2853204;
Nearest TSS
ENST00000527297/Upstream/13087; ENST00000325719/Downstream/4626;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/193550, chr11-CpG: 34/Downstream/226306
Nearby gene
TRIM21
Upstream sequence
caaaatGTGTGTGTGTGTGTATGTATCAATCTCAAGATTGAGCTAATTATACTCTTTGTTTCATCACTGATCCATGTACAGTCTCATTTATTTATTTAtt
Downstream sequence
ttaatataatctatttaaatattaaaatataaatCCCACAACATTAAGGTAGTTGCAAACATCTCTAAACTCCCTCACCCCTGCTTCTAGTTCCATATCA
Target sequence
AGGTGTCTCCAAAGTTTACTCCATACATTTTTACTAAGCATCTGCTAAATTCAGATGAATCTCCAACAAATAATTGAATACTATGGtaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate