Basic Information
VIS ID
TVIS10019354
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
88719739/88325962 (Hg38)
End
88719739/88325962 (Hg38)
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/1580813; hsa-mir-1178/Downstream/6235827;
Nearest TSS
ENST00000382841/Upstream/183655; ENST00000625763/Downstream/208800;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/183591, chr12-CpG: 104/Downstream/253721
Nearby gene
KITLG
Upstream sequence
TGCTACAAGAGTAAGGCTACTGAGGTTGAGATGCAAGAGCTTTGTGCTGGGGGGCCACAAGACAGAGCAGATCCGGAATCCAGGCAACCTTCACTTCCAG
Downstream sequence
TAATGCCTGAGCTTCAAAATAAGGAAAGGAGAATAGAAGCTCTGTGGTATCAGGGCTGAACATGATCACACAATGCAAAGGGAAACAATACTTAGTGTTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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