Fusion event
HBV-GCOM1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
57968468/57676270 (Hg38)
Nearest miRNA
hsa-mir-10393/Upstream/2303147; hsa-mir-11181/Downstream/1494913;
Upstream sequence
GGGAGTGAAAGGAAGAGAGCTTTAGTAAGTAAAGTGAGGATCACCATTTCCATATGCAGAATGGGCTTTCAAACACAGACTACAAAGACCCATGGTTTTA
Downstream sequence
CCATTCTCAAAGAATTTACCAAAAGCGGCATTAGGTTCTTTCTTTGACAGTGTCCTCAATTACATTGCTTGCCTTCTAGTAAAAAGGCATTTTTTATCAG
Target sequence
cattgtaCAGTAAGGCCTCCTTTCCTTACtttattaatttttatttattaCTGGTATTGTCATTTTTGTTAATTAAAATGAATCACTTG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.