Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019375
Fusion event
HBV-SPIRE2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
Start
End
89903145/89836737 (Hg38)
Location type
Intron1
Target gene
miRNAs that regulate target gene
hsa-mir-6778-3p ; hsa-mir-3137 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-4279 ; hsa-mir-6749-3p ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-498 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4532 ; hsa-mir-1247-3p
Nearest miRNA
hsa-mir-11401/Upstream/1120400;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1473, chr16-CpG: 57/Downstream/13505
Upstream sequence
ttgtatttgcctgatgattagtgatgttgagcattttttcatgttttttggccatttgtatttctttttttgagaaatgtctgttcatgtcatttgccca
Downstream sequence
gggaggccaaggcaggcggatcacctgaggtcgggagttcgagaccagcctgaccaacatggagaaaccccgtctctactgaaaaaaaaaaaaaagaaaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.