Basic Information
VIS ID
TVIS10019378
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
44597418/46520052 (Hg38)
End
44597418/46520052 (Hg38)
Location type
Intron
Target gene
ARL17A ; LRRC37A2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-1180/Upstream/1044617; hsa-mir-10226/Downstream/452965;
Nearest TSS
ENST00000595228/Upstream/7342; ENST00000572638/Downstream/27173;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/146806, chr17-CpG: 71/Downstream/59072
Upstream sequence
TTTTGTAAGAATAAGCCACAGTTTACCCTCACAAGCTTCCATTCTTGGCTCAGGTATTAGAGTCAGGTGCCACAGGTATATAATGAACCGGCAGATCTGG
Downstream sequence
AAAAGGAAAATATAAGAAAAGGTTTGAATGAAAGCAGAGCAGATCCCACCATCTTGAAGTGACCATGACCCAGCTTTCCTCCACATGCAGGAGATGGTTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate