DYM _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019380
Fusion event
HBV-DYM integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
46917122/49390752 (Hg38)
End
46917122/49390752 (Hg38)
Location type
Intron14
Target gene
DYM
miRNAs that regulate target gene
hsa-mir-941 ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-106a-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-223-5p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p
Nearest miRNA
hsa-mir-1-2/Upstream/340984; hsa-mir-122/Downstream/96621;
Nearest TSS
ENST00000575820/Upstream/12103; ENST00000581232/Downstream/21189;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/414146, chr18-CpG: 74/Downstream/69382
Upstream sequence
AGTAGATCACAACACATCTAACTGCTGTATCCCCatataaaataattttaattttCCTAGACTGCAGAATTGATCACATTTACTGATGATGGATTGGGAA
Downstream sequence
catcagcctctcaaaatgctgggattataggcgtgagccactgtgtccggccTAGACAGCCTGATTTTAAAACAGAATATTGTTCTCACTTATTACATTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate