Basic Information
VIS ID
TVIS10019382
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
56083448/58416216 (Hg38)
End
56083448/58416216 (Hg38)
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/2936918; hsa-mir-122/Downstream/34858;
Nearest TSS
ENST00000575820/Upstream/16134; ENST00000585470/Downstream/549;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/159380, chr18-CpG: 92/Downstream/254763
Nearby gene
MIR122
Nearest cancer related gene
MIR122(TSG, No orient)
Upstream sequence
TTGTTGACACAGTGTACCTCAAGTATTGGAGGGAGATGGCCTCGGTATAACTCTTTGTCCTAACATTTATTGATAAGAATCATCTGGTTGGAAGGCCCTT
Downstream sequence
AAGAGCGAGGTGCTGGAAGAGAGGCCCTATCTGGAGAACAGAGTGCAGAGAACACCTGTCCCCCAGGGTGGGGTGGGCCTGACCCTCACGAACCATGCTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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