Basic Information
VIS ID
TVIS10019387
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
56503850/55992484 (Hg38)
End
56503939/55992573 (Hg38)
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/604242; hsa-mir-10394/Downstream/2342115;
Nearest TSS
ENST00000633603/Upstream/44581; ENST00000597673/Downstream/7153;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/134181, chr19-CpG: 178/Downstream/94099
Nearby gene
NLRP5
Upstream sequence
acactgtcagaatgacaaggtgggagaaagacccaactagccactgctggctctgaagatggaggaagggaccaggagctggagggtgcaggcagcctct
Downstream sequence
TTCTCTGTAGGGCTTGTgtcaaatccagcccattgcccagttttgtaaataaagatttattggaacacagcttttctcctttgttgacaaattgtctaca
Target sequence
acagtgtataagctttccattttttcctgcaacctcagcagcgtcggttttttgactttttaataatGACACGTAACATTCTTATGGGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate