Basic Information
VIS ID
TVIS10019399
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
15489583/15471460 (Hg38)
End
15489583/15471460 (Hg38)
Location type
Intron
Target gene
PIR ; PIR-FIGF
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-3690-1/Upstream/1881114; hsa-let-7f-2/Downstream/1155552;
Nearest TSS
ENST00000429181/Upstream/7214; ENST00000463891/Downstream/19747;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/135574, chrX-CpG: 35/Downstream/21728
Nearest cancer related gene
PIR(OG, No orient, 0)
Upstream sequence
ttataattttttttttttttttttttttttggagacggagtttcacttttgttgcccaggctggaatgcaatggtgcaatcttggctcactgcaacctcc
Downstream sequence
GAGATCAAGCTTGGGCTTCGAAGCTTGGGCCTTCCCCAATAATGGCCCAACCTAAAATTTTAGACCCTATAATACTCCTCCACCTCCCATCCTTCCACAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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