Basic Information
VIS ID
TVIS10019402
Fusion event
HBV-LINC00486 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
33091944/32866877 (Hg38)
End
33092034/32866967 (Hg38)
Location type
Intron2
Target gene
LINC00486
Nearest miRNA
hsa-mir-1301/Upstream/231546; hsa-mir-10b/Downstream/551549;
Nearest TSS
ENST00000437798/Upstream/25863; ENST00000435075/Downstream/15834;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/238674, chr2-CpG: 164/Downstream/79414
Upstream sequence
CCCGTCCGTCCTTATTCCTTCCACTTACTTGTCTAGAATCAATGGAAATGTGGACCTCGGGAAATGTGGTCTTTCCCAGCTCCTCCCTGGGAGACAAGCA
Downstream sequence
tttttttctcttctttttttttttttttttttttttctttttttttttcttctttctttttctctcttttttttttcttttttcttttttcttttttttt
Target sequence
ttttttcttttctttttttttttttttttttttcttttttttttttttttttttttttttttcttttttttttttctttttttttttttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate