Fusion event
HBV-chr12 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
66451462/66057682 (Hg38)
Nearest miRNA
hsa-let-7i/Upstream/33867; hsa-mir-1178/Downstream/193400;
Upstream sequence
AGTGAAGATTTTGATTATAAGGAAACGTGGATGTATATGTGCTTGTGTCTCTGTGTGTGTGTGTTGTTGGGGGAAGCAGGGTGCAATCAGTGATGTAAAA
Downstream sequence
gagacggagtctcactctgttgcccagactggagtacaatgctacaatcttggctcactgcaacctctgcctcccaggtgcaaacaattctcctgcctca
Target sequence
ttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttt
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.