Fusion event
HBV-LINGO1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
77910960/77618618 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10393/Upstream/1856213; hsa-mir-11181/Downstream/1591170;
Upstream sequence
AACTAAACAGCTGAAAGCAAGGGCCAGATAATTGTCTGGTGGTGGTGATCACGGACTCCTCAGCCATTGCCAGCCACATTTATCCTCAGAGATTTTCACT
Downstream sequence
tcgctctgtcgcccaggctggagtgcagtggcgggatctcggctcactgcaagctccgcctcccgggttcacgccattctcctgcctcagcctcccaagt
Target sequence
tttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttttgagacggagtc
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.