Basic Information
VIS ID
TVIS10019413
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1263560/1263561 (Hg38)
End
1264325/1264326 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
LOC105372236 ; LOC107985303
Nearest miRNA
hsa-mir-1302-11/Upstream/449908; hsa-let-7e/Downstream/551833;
Nearest TSS
ENST00000633603/Upstream/1740; ENST00000592815/Downstream/2327;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2226, chr19-CpG: 336/Downstream/1529
Nearby gene
CIRBP-AS1
Upstream sequence
AGCTGTAATGCTTTTTTCTTTTTATAACCCAAAAAGCAGGTATGTCAGTCGCTTTTTCTGCCCACAATGATAAATTAAAAACAGCCACTATCCATTTGGA
Downstream sequence
atgagccagcgctcccggccTGCATACGGGATGATTCCATGTGGACTGCCACATCAAGGAAGCAAACAACAAGGAAAGCCTGGCGCTGCGTGGAGCTGTC
Target sequence
GTGCATGTTGGAAATACAAATGAAACAGGAGAGTTAGCATACGGGACAAttattatttttgtttgtttttgttttgagacggagtctcgctctgtcgccctggctggagtgcattggcgcgatctcggctcaccgcaacctctgcctcccgggttcaagtgattctcctgcctcagcctctggagtagctgggattacaggcgcccgccaccacgcccggctaatttttgtatttttttagtagagacgggcttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate