Basic Information
VIS ID
TVIS10019422
Fusion event
HBV-ANKRD30BL integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
132997488/132239915 (Hg38)
End
132997577/132240004 (Hg38)
Location type
Intron4
Fragile sites / regions
FRA2S
Target gene
ANKRD30BL
Nearest miRNA
hsa-mir-1285-2/Upstream/748679; hsa-mir-10b/Downstream/16962;
Nearest TSS
ENST00000437798/Upstream/77960; ENST00000622084/Downstream/17965;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/201104, chr2-CpG: 23/Downstream/14035
Upstream sequence
TTATGATAAATGATCAATCATATTAATCAGATAATTGACCCATCAGCTGTAAAGTGTGAACCATGTTTACACCCAAGTTTTATTCCCAGTGGTGTAAATG
Downstream sequence
ttctcagaaacttcttgtgatgtttgcattcaactcacagagttgaacattccttttcatagagcagttatgaaacactcttttagtagaatctacaagt
Target sequence
tttttgtagaatctgcaagtggacatttggatagctttgaggatttcgttggaaacgggaatatcttcacataaaactagacagaagca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate