Fusion event
HBV-ITIH4 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
52855146/52821130 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/526322; hsa-mir-12124/Downstream/25333;
Upstream sequence
ggttttggccagcttctttacttgcaacctgttttatcagcaaggtctttatgacctgtatcttgtgctgacctcctatcttatcctgtgacttagaatg
Downstream sequence
CTGGAAAGAGGGGCCCAGCCAGGGCAGGAGCAGTGAGGGCCGGACATCTGCATCTGCCTGGCACTTCTGAGCTCTTCCATGATTGGGGCTGGGGCAGGTC
Target sequence
CGCCTTCCATGGGCTTCTCAGCAACTTGAGACTGCTCTTGGTCATCGGGTTTGGTGACTACCATAGATGTGAGAGGCGTGACAAAGCTGTAGGCAAGTGATAAATTCAGCGCTTGGTTCCGGAGGGCCTGCTGATCAGCATCGGATGCGGAGACACTGTAGGTGGAGCACATCAGAGCTCAGGAGATCCTTGAATTCGGGAACAGATTTTCCATCCAGCCCCTTCTGGGGAGGTCCCTCTGGGAGAATCTGGAGC
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.