MAGI1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019427
Fusion event
HBV-MAGI1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
65994469/66008794 (Hg38)
End
65994558/66008883 (Hg38)
Location type
Intron22
Target gene
MAGI1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-24-3p ; hsa-mir-324-3p
Nearest miRNA
hsa-let-7g/Upstream/5390924; hsa-mir-12124/Downstream/1216581;
Nearest TSS
ENST00000440867/Upstream/101119; ENST00000484768/Downstream/29425;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/459125, chr3-CpG: 158/Downstream/28815
Upstream sequence
TCAAGGCAAAAGTCCTTTAAATTTTCATTTCAATATTGAGAATTATTAATACTATGTGATCACCAGAAATAAGAGAGTTAGCAATGGTTGTTGGTGAGGG
Downstream sequence
ccctgagaggctttaagcagggTATGCCAGGTTAGAGAAAAGAAGGTATAGGCAGATCCCAGGAATTTTACTGAGGAAGCAGGTCTCAGACCCCAGCTAT
Target sequence
CATGTACAATGAAGCTGGCCGGGGGGCAggggccagaccatgagggctcttgtagctctaaatactttgatcctaagaacagagagaag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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