Basic Information
VIS ID
TVIS10019428
Fusion event
HBV-MTRNR2L12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
96336292/96617448 (Hg38)
End
96336573/96617729 (Hg38)
Location type
Intronic
Target gene
MTRNR2L12
Nearest miRNA
hsa-let-7g/Upstream/257409; hsa-mir-12124/Downstream/3346585;
Nearest TSS
ENST00000440867/Upstream/1654518; ENST00000506569/Downstream/507;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1679133, chr3-CpG: 49/Downstream/159044
Nearby gene
EPHA6
Upstream sequence
ctgaggcaggagaattgcttgaacccgggagacagaggttgcagtgagccacgatcgcgccactgcactccagcctgggcgacagcaagactctgtctca
Downstream sequence
GGCCTACTATGGGTATTAAATTTTTTACTCTCTTTACAAGGTTTTTTCCTAGTGTCCAAAGAGCTGTTCCTCTTTGGACTAACAGTTAAATTTACAAGGG
Target sequence
TAACCTTTCCTTGTGGGCATGCCTGTGTTGGGTTAACAGTGAGGGTAATAATGGCTTGTTGGTTGATTGTAGATATTGGGCTGTTAATTGTCAGTTTAATATTTTGGTCTGATGTAGGCTTATGCGGAGGAGAATGTTTTCATGTTACTTATACTAACATTAGTTCTTCTATAAGGTAATAGATTGGTCCAATTGAGTGTAAGGAGCTCAGTTGTATGTTTGGGATTTTTTAGACGATGGGTGTTGAGCTTGAAC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate