Basic Information
VIS ID
TVIS10019429
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100212130/99290973 (Hg38)
End
100212130/99290973 (Hg38)
Location type
Intron7,Exon9
Target gene
ADH1A ; LOC100507053
miRNAs that regulate target gene
hsa-mir-132-3p
Nearest miRNA
hsa-mir-12113/Upstream/293513; hsa-mir-1243/Downstream/1949822;
Nearest TSS
ENST00000502981/Upstream/37; ENST00000503257/Downstream/10;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/201995, chr4-CpG: 40/Downstream/272597
Upstream sequence
ACTTTTCACCCTAAAAGAAAATGATCTTCTTGTCCAGGAGTTGGAATAATTGGGCTACAGAGACTGAAGTCCTATGCCTCTCAACTTCTTGCTCATATAC
Downstream sequence
GCTCAAGTGCATAAAGCAGGTGTATTGCATAGGTATTTATTTATTTTTTTTGCTTGAATAACACCCGATTCCAGTTCCACACATGATCTAGGTCTTTAAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate