Basic Information
VIS ID
TVIS10019430
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100226387/99305230 (Hg38)
End
100226412/99305255 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/307770; hsa-mir-1243/Downstream/1935540;
Nearest TSS
ENST00000502981/Upstream/14202; ENST00000503257/Downstream/13612;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/216252, chr4-CpG: 40/Downstream/258315
Nearby gene
ADH1B
Upstream sequence
TTCCCCAGGATTTTGTTTTTATACAGGGACAAggcagtgtaaattcacacaaccttttggaaagcagtttggcagcatgtaccaaaaaagacataaaaca
Downstream sequence
CATGCTCAGAATTTCATTTTAAATATGTTCGTGATATTATTGAAGTCACCCCCCCCCACTTTATTTGTTTTCATATATCATGAGAAGTCAAAGAATCAAA
Target sequence
TATACCAGAATTTGAAATTTTTCTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate