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VISDB
Viral Integration Site DataBase
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TVIS10019436
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019436
Fusion event
HBV-RPL30 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr8
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
99053999/98041771 (Hg38)
End
99054079/98041851 (Hg38)
Location type
Exon1
Fragile sites / regions
FRA8B
Target gene
RPL30
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-346
;
hsa-mir-320a
;
hsa-mir-93-5p
;
hsa-mir-20a-5p
;
hsa-let-7a-5p
;
hsa-mir-19b-2-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-7856-5p
;
hsa-mir-450b-5p
;
hsa-mir-6516-5p
;
hsa-mir-6811-5p
;
hsa-mir-4477b
;
hsa-mir-6511b-5p
;
hsa-mir-657
;
hsa-mir-3665
;
hsa-mir-125a-3p
;
hsa-mir-4748
;
hsa-mir-4464
Nearest miRNA
hsa-mir-12123/Upstream/2968775; hsa-mir-10400/Downstream/351794;
Nearest TSS
ENST00000518652/Upstream/45;
ENST00000318528/Downstream/1234;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/172156
,
chr8-CpG: 17/Downstream/3458
Upstream sequence
gcgttttctcctaaaagttttatagttttagcttttaagtttaggtctttgatccattttgagttaatttttgtaaatggtatgtataaggtaagagtct
Downstream sequence
taaaaaataaaaataaaaaaaCAGTAATTTTACAATTCATTTAATAGCAACTGGTACCATAAAATTTCTCTACCTTTGGTTATCCCTTCTGTAGACAATG
Target sequence
TGCAGGTGAAATTTTGTAGGTGAAAAGGTTTACTTTTCACCAGTCTGTTCTGGCATGCTTCTAATGATGTCAGAGTCACC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Sample Information
×
Sample name
22T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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