Basic Information
VIS ID
TVIS10019437
Fusion event
HBV-LDHAP4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
14921580/14921582 (Hg38)
End
14922125/14922127 (Hg38)
Location type
Intronic
Target gene
LDHAP4
Nearest miRNA
hsa-mir-101-2/Upstream/8913678; hsa-let-7a-1/Downstream/3651179;
Nearest TSS
ENST00000422679/Upstream/10587; ENST00000461041/Downstream/265938;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/228004, chr9-CpG: 41/Downstream/55969
Nearby gene
LOC389705
Upstream sequence
gccagtgtgactggagtagggaggtcaagggagagcatatggagcataccggagtagggaggtcaagggagagcaTGGTATTGGACGAAGTGATAAGATG
Downstream sequence
GCTGCCATGTTGGAGATCCATCATCTCTCCCTTCAATTTGTCTTCGATGACATCAACAAGATCAAGTTCATCTGCCAAGTCCTTCATTAAGATATTGATG
Target sequence
GCCCAGGATGTGTAGCCTTTGAGTTTGATCACCTCATAAGCACTCTCAACCACCAGTTTGTGAACCTCTTTCCACTGTTCCTTATGTTTATCAGTCTCTAAATCTGGGTGCGGAGTCTTCAGGGAGACACCAGCAACATTCTTTCCACTCCATACAGGTGCACTGGAATCTCCATGTTCCCCAAGGACCCACCCATGACAGCTTAATGGGTGAACTCCCAGCCTTTCCCCCATCAGGTAACGGAATTGGGCTGAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate