AMBP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019439
Fusion event
HBV-AMBP integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
GRCh37/hg19
Start
116824956/114062676 (Hg38)
End
116825038/114062758 (Hg38)
Location type
Exon4
Fragile sites / regions
FRA9E
Target gene
AMBP
Nearest miRNA
hsa-let-7a-1/Upstream/2130507; hsa-mir-12126/Downstream/146676;
Nearest TSS
ENST00000422679/Upstream/34755; ENST00000451716/Downstream/12211;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/12567, chr9-CpG: 104/Downstream/35282
Upstream sequence
GGCTGCTGGGGCTTCCCCTTTCGACCCCTGCCTAGCCATGCCTCGATTCTATTCCCTTCTCTACCTCGCCACTATCCCCTCACCATCAGAACCTCTCTGT
Downstream sequence
CTGCGGGGGAGAGAAAGAGAAGAAGCAGTTGCAGACTCCTTGCCGCTATTGCTTTCCTGTACCCCTGGAATATATAAATGAACAACTTGCTTTGGGAATC
Target sequence
CTTCTTTCTTGGTGACTTCAGTTACCAGTTGCCCACCCCCTGATCCTTCCTCTTCTTGGGGTAGCACAGCCCTCCGGACTCT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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