Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019440
Fusion event
HBV-NUP214 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
End
134106072/131230685 (Hg38)
Location type
Exon34
Target gene
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-193b-3p ; hsa-mir-331-3p ; hsa-mir-328-3p ; hsa-mir-149-5p ; hsa-mir-15b-5p ; hsa-mir-22-3p ; hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-6515-3p ; hsa-mir-520f-5p ; hsa-mir-216b-5p ; hsa-mir-618 ; hsa-mir-548c-3p ; hsa-mir-1236-3p ; hsa-mir-6847-3p ; hsa-mir-767-3p ; hsa-mir-133b
Nearest miRNA
hsa-let-7a-1/Upstream/604322; hsa-mir-126/Downstream/1715022;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/104766, chr9-CpG: 17/Downstream/30140
Nearest cancer related gene
NUP214(OG, No orient, 0)
Upstream sequence
GGGGCAGAAGTGACCCAAGAAGATGGGTCATTGGTGTGTCTTTATGTAACAGAGCATGAAGACGTATAAAGTTACATTCACTTATATGCATACAGAGATA
Downstream sequence
GTTTCATTAAAAGTGAACCATCCTATTGGTTTGTATGCAACCTAGATCATTTAATTTTATGCTAAAAAAAAAAGCTCAGACGTTGTTTGCAGTCCTATGT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.