A2M _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019448
Fusion event
HBV-A2M integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
9222409/9069813 (Hg38)
End
9223083/9070487 (Hg38)
Location type
Exon4
Target gene
A2M
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-141/Upstream/2105622; hsa-let-7i/Downstream/168980;
Nearest TSS
ENST00000382841/Upstream/735; ENST00000427111/Downstream/9911;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/4694, chr12-CpG: 18/Downstream/169376
Upstream sequence
atcaatcattgactgtaatcccagcactttgggaggccgaggcagggtggatcacgaggtcaggagattgagaccatgctagctaacacgttggaacccc
Downstream sequence
CATTTTCACTGTTGGCTTCAGGGGAATGAAGCCAGAGACCATCTTCACATCAACGATCGCCATGTTGGAGGCAGAGCGGCTCCCTGTGTAACTGAGGATC
Target sequence
CTGAAGAAAATTGAAATACCACAAATGTTAATAAATAGATGAAACCCCTGGGGGATCCAGAGAAAAAATCTTTGTATTGCCAAAATAACCCTGAGGGTAGAATTCTTCAAATGCTTTTTGTAAGGAAATATATAATGTAATACAATTAAAAATGAAAGGCATAAAGGGTTTACTATTAGTATAACACACGACTAATGTGTAAAGTTATTTATCTGAAGAAAAGACAGCTAAGTATCCTAAACTTGGTAGTTACTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate