Basic Information
VIS ID
TVIS10019450
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr12
Cytoband
q24.22
Reference genome
GRCh37/hg19
Start
116985468/116547663 (Hg38)
End
116985557/116547752 (Hg38)
Fragile sites / regions
FRA12E ; FRA12C
Nearest miRNA
hsa-let-7i/Upstream/119345; hsa-mir-1178/Downstream/3165882;
Nearest TSS
ENST00000382841/Upstream/29805; ENST00000630062/Downstream/353;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/38861, chr12-CpG: 65/Downstream/190066
Nearby gene
MAP1LC3B2
Upstream sequence
tatcatacaattggaatcatacagtatgtagccttttcggatcagcttctttcacttagtaaaatgcatataagttatctttatgtgttttcatggcttg
Downstream sequence
gaaccgtaacttaattacatctgcaaagaccattttcccaaataagttcttattcacagattctgaggaagggtggttgtacatggatatatttgtgggg
Target sequence
ctggcctctcttgtctgtgtctcttccaaagacacttgtcgcgttggagttaaggcccacccagataatctgggatgatctcatttcga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate