Fusion event
HBV-chr14 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
43774843/43305640 (Hg38)
Nearest miRNA
hsa-mir-208a/Upstream/6353160; hsa-mir-1185-1/Downstream/4455355;
Upstream sequence
CTCTCTCTCTCTCTCCatatatatatgtatgtctctctccatatatatatatatgtgtgtgtatatatatatacacacacacatatacacacatatacat
Downstream sequence
TATGCTAGTTTTCGTCATAGTCTCCTTAGGTATTACCAAACTTTTTTGTATGCCATGGTTGCATttagctgaactaaggaaaagtcctgcaaccacaaaa
Target sequence
TTAGAACATGAAACTTTCCAAACAGAATATATTTGTTAATGGGTTGAAAATAAATAGAAGTGGGTAGTGGTAAGCTACTAGGTCATTAT
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.