VISDB Viral Integration Site DataBase

VIS ID

TVIS10019458

Fusion event

HBV-SRRM2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr16

Cytoband

p13.3

Reference genome

Start

End

2820855/2770854 (Hg38)

Location type

Intron14

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-26b-5p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-505-5p ; hsa-mir-769-3p ; hsa-mir-769-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-504-5p ; hsa-mir-324-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-31-5p ; hsa-mir-25-3p

Nearest miRNA

hsa-mir-1225/Upstream/238713; hsa-mir-11401/Downstream/714527;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/3924, chr16-CpG: 130/Downstream/5906

Upstream sequence

CGACCTTGACCTCTGCTGTGAAGGTCTCACCGCcctggagagctgtgaaaaatatcccccggccgggggcggtggctcacgcctgtcatcccagcacttt

Downstream sequence

CAGGTCTCCATAAATTGTCTTTGGGGGATTCCACCACACCCAATGCTCTGGAGCCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGCCGTGGGAGGGTCCT

Target sequence

TGCGTGTCCTGGAAGGCTGATGCCCCCTTCCGGGAGCCAGTTGTGGTGGTGGGTGGCGGCCCCATTTTGGGAGTGGCCCAGAAACTGGCCTTGAGGGCTGGGGTGGGAACTCCCTGTTGACCCATATCTTCTCTTG