PHKB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019459
Fusion event
HBV-PHKB integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
47538729/47504818 (Hg38)
End
47538779/47504868 (Hg38)
Location type
Intron5
Target gene
PHKB
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-484 ; hsa-mir-6882-3p ; hsa-mir-4312 ; hsa-mir-100-3p ; hsa-mir-4258 ; hsa-mir-1265
Nearest miRNA
hsa-mir-1225/Upstream/13341145; hsa-mir-11401/Downstream/2787748;
Nearest TSS
ENST00000527434/Upstream/5062; ENST00000566436/Downstream/89282;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/43522, chr16-CpG: 31/Downstream/739553
Upstream sequence
GGGTTCCCGGAGAGGCCAGCGTGGGGACAGCCGCTCCCCCAGCCACAAGCGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCTCCTCCAGG
Downstream sequence
catctcacccagggcggtgccccagaggtggagcaccagggcacgtgttaggacctgaaagatgatgaactgtgcctggtcagggcaaagctggaggaaa
Target sequence
gaggtgggatcccgaggcctctccagtcccctgagggtgcaccactggcc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate