Fusion event
HBV-ASPSCR1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
79968743/82010867 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10226/Upstream/316930; hsa-mir-4525/Downstream/225801;
Nearest cancer related gene
Upstream sequence
ctcctgacTGCCTTTCTCTACTTTTCCTAACCTCCAGCCTAGGTCTAGTTTTAGTATTAACTTCTAATATATATTCCTAAATTACTTCTTGACTAGCTTA
Downstream sequence
GGTGGGCAGCGCTGTGGGGTGTCCGGGGATGGGGGGCAGGGGCCCATGGGGCCTCTCCCGGCTCCTTCCTTCCAGGCCACAGGACTGCAGCCACCTGGCC
Target sequence
AGGTGGCTCTGAGGGTCCTGTTCCCCGACCGCTACGTCCTACAGGGCTTCTTCCGCCCCAGCGAGACA
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.