Fusion event
HBV-APOE integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
45412650/44909393 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/149809; hsa-let-7e/Downstream/527261;
Upstream sequence
cgttctgttcagcacagacctggggggttagggttaggggtgccgttggggttggggttggggttagggttaggggttagggttagggttagggtttagg
Downstream sequence
TCTGCTGGCCTCCCCCTGTGATTTCCTCTAAGCCCCAGCCTCAGTTTCTCTTTCTGCCCACATACTGGCCACACAATTCTCAGCCCCCTCCTCTCCATCT
Target sequence
AGGGCGCTGATGGACGAGACCATGAAGGAGTTGAAGGCCTACAAATCGGAACTGGAGGAACAACTGACCCCGGTGGCGGAGGAGACGCGGGCACGGCTGTCCAAGGAGCTGCAGGCGGCGCAGGCCCGGCTGGGCGCGGACATGGAGGACGTGTGCGGCCGCCTGGTGCAGTACCGCGGCGAGGTGCAGGCCATGCTCGGCCAGAGCACCGAGGAGCTGCGGGTGCGCCTCGCCTCCCACCTGCGCAAGCTGCGT
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.