Basic Information
VIS ID
TVIS10019469
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42524781/42128779 (Hg38)
End
42524781/42128779 (Hg38)
Location type
Intron
Fragile sites / regions
FRA22A
Target gene
CYP2D6 ; LOC101929829
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1281/Upstream/205482; hsa-let-7a-3/Downstream/3072175;
Nearest TSS
ENST00000624155/Upstream/37824; ENST00000626627/Downstream/1130;
Nearest CpG islands
chr22-CpG: 95/Target, None/Upstream, None/Downstream
Upstream sequence
CCCAAACCCATCTATGCAAATCCTGCTCTTCCGAGGCCCCAGTCCAGCCCCGGCACCTCTCGGGAGCTCGCCCTGCAGAGACTCCTCGGTCTCTCGCTCC
Downstream sequence
GCACCTCGCGCAGAAAGCCCGACTCCTCCTTCAGTCCCTCCTGAGCTAGGTCCAGCAGCCTGAGGAAGCGAGGGTCGTCGTACTCGAAGCGGCGCCCGCA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate