Basic Information
VIS ID
TVIS10019470
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42526613/42130611 (Hg38)
End
42526613/42130611 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA22A
Target gene
CYP2D6 ; LOC101929829
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1281/Upstream/207314; hsa-let-7a-3/Downstream/3070343;
Nearest TSS
ENST00000624155/Upstream/702; ENST00000626627/Downstream/194;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/705, chr22-CpG: 101/Downstream/11849
Upstream sequence
CTGGCTTCTGGTCCAGCCTGTGGTTTCACCCACCACCCATGTTTGCTGGTGGTGGGGCATCCTCAGGACCTCTGCCGCCCTCCAGGACCTCCTCCCTCAC
Downstream sequence
CTGGTCGAAGCAGTATGGTGTGTTCTGGAAGTCCACATGCAGCAGGTTGCCCAGCCCGGGCAGTGGCAGGGGGCCTGGTGGGTAGCGTGCAGCCCAGCGT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate